T cell metabolic reprogramming in acute kidney injury and protection by glutamine blockade

T cells play an important role in acute kidney injury (AKI). Metabolic programming of T cells regulates their function, is a rapidly emerging field, and is unknown in AKI. We induced ischemic AKI in C57BL/6J mice and collected kidneys and spleens at multiple time points. T cells were isolated and an...

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Detalles Bibliográficos
Autores principales: Lee, Kyungho, Thompson, Elizabeth A., Gharaie, Sepideh, Patel, Chirag H., Kurzhagen, Johanna T., Pierorazio, Phillip M., Arend, Lois J., Thomas, Ajit G., Noel, Sanjeev, Slusher, Barbara S., Rabb, Hamid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371253/
https://www.ncbi.nlm.nih.gov/pubmed/37166984
http://dx.doi.org/10.1172/jci.insight.160345

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371253/
https://www.ncbi.nlm.nih.gov/pubmed/37166984
http://dx.doi.org/10.1172/jci.insight.160345

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