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TSLP/dendritic cell axis promotes CD4(+) T cell tolerance to the gut microbiome

Thymic stromal lymphopoietin (TSLP) overexpression is widely associated with atopy. However, TSLP is expressed in normal barrier organs, suggesting a homeostatic function. To determine the function of TSLP in barrier sites, we investigated the impact of endogenous TSLP signaling on the homeostatic e...

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Detalles Bibliográficos
Autores principales: Messerschmidt, Jonathan L., Azin, Marjan, Dempsey, Kaitlin E., Demehri, Shadmehr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371333/
https://www.ncbi.nlm.nih.gov/pubmed/37427591
http://dx.doi.org/10.1172/jci.insight.160690