The MIF promoter SNP rs755622 is associated with immune activation in glioblastoma

Intratumoral heterogeneity is a defining hallmark of glioblastoma, driving drug resistance and ultimately recurrence. Many somatic drivers of microenvironmental change have been shown to affect this heterogeneity and, ultimately, the treatment response. However, little is known about how germline mu...

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Detalles Bibliográficos
Autores principales: Alban, Tyler J., Grabowski, Matthew M., Otvos, Balint, Bayik, Defne, Wang, Wesley, Zalavadia, Ajay, Makarov, Vlad, Troike, Katie, McGraw, Mary, Rabljenovic, Anja, Lauko, Adam, Neumann, Chase, Roversi, Gustavo, Waite, Kristin A., Cioffi, Gino, Patil, Nirav, Tran, Thuy T., McCortney, Kathleen, Steffens, Alicia, Diaz, C. Marcela, Brown, J. Mark, Egan, Kathleen M., Horbinski, Craig M., Barnholtz-Sloan, Jill S., Rajappa, Prajwal, Vogelbaum, Michael A., Bucala, Richard, Chan, Timothy A., Ahluwalia, Manmeet S., Lathia, Justin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371339/
https://www.ncbi.nlm.nih.gov/pubmed/37252795
http://dx.doi.org/10.1172/jci.insight.160024

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