Specific regulation of mechanical nociception by Gβ5 involves GABA-B receptors

Mechanical, thermal, and chemical pain sensation is conveyed by primary nociceptors, a subset of sensory afferent neurons. The intracellular regulation of the primary nociceptive signal is an area of active study. We report here the discovery of a Gβ5-dependent regulatory pathway within mechanical n...

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Detalles Bibliográficos
Autores principales: Pandey, Mritunjay, Zhang, Jian-Hua, Adikaram, Poorni R., Kittock, Claire, Lue, Nicole, Awe, Adam, Degner, Katherine, Jacob, Nirmal, Staples, Jenna, Thomas, Rachel, Kohnen, Allison B., Ganesan, Sundar, Kabat, Juraj, Chen, Ching-Kang, Simonds, William F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371342/
https://www.ncbi.nlm.nih.gov/pubmed/37219953
http://dx.doi.org/10.1172/jci.insight.134685

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