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MYC regulates CSF1 expression via microRNA 17/20a to modulate tumor-associated macrophages in osteosarcoma

Osteosarcoma (OS) is the most common primary bone tumor of childhood. Approximately 20%–30% of OSs carry amplification of chromosome 8q24, which harbors the oncogene c-MYC and correlates with a poor prognosis. To understand the mechanisms that underlie the ability of MYC to alter both the tumor and...

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Detalles Bibliográficos
Autores principales:	Nirala, Bikesh K., Patel, Tajhal D., Kurenbekova, Lyazat, Shuck, Ryan, Dasgupta, Atreyi, Rainusso, Nino, Coarfa, Cristian, Yustein, Jason T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371352/ https://www.ncbi.nlm.nih.gov/pubmed/37279073 http://dx.doi.org/10.1172/jci.insight.164947

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