Targeted Transcriptional Analysis of IgA Vasculitis, IgA Nephropathy, and IgA-Dominant Infection-Related Glomerulonephritis Reveals Both Distinct and Overlapping Immune Signatures

KEY POINTS: Skin IL-9, calprotectin, and KIR gene expression may be predictive of subsequent kidney involvement in patients with IgAV. Histologically similar patients with IgAN, IgAV, and IgA-IRGN can be distinguished by their immune transcriptomes. Kidney biopsies from patients with IgA-IRGN are en...

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Detalles Bibliográficos
Autores principales: Kung, Vanderlene L., Avasare, Rupali, Friedman, Marcia A., Koon, Stephanie Mengden, Neff, Tanaya L., Protzek, Sara, Corless, Christopher, Krajbich, Victoria, Setthavongsack, Naly, Ditmore, Rebecca, Woltjer, Randall, Andeen, Nicole K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Nephrology 2023
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371378/
https://www.ncbi.nlm.nih.gov/pubmed/37036681
http://dx.doi.org/10.34067/KID.0000000000000123

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