Addition of heparin binding sites strongly increases the bone forming capabilities of BMP9 in vivo

Bone Morphogenetic proteins (BMPs) like BMP2 and BMP7 have shown great potential in the treatment of severe bone defects. In recent in vitro studies, BMP9 revealed the highest osteogenic potential compared to other BMPs, possibly due to its unique signaling pathways that differs from other osteogeni...

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Detalles Bibliográficos
Autores principales: Siverino, Claudia, Fahmy-Garcia, Shorouk, Niklaus, Viktoria, Kops, Nicole, Dolcini, Laura, Misciagna, Massimiliano Maraglino, Ridwan, Yanto, Farrell, Eric, van Osch, Gerjo J.V.M., Nickel, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371762/
https://www.ncbi.nlm.nih.gov/pubmed/37502679
http://dx.doi.org/10.1016/j.bioactmat.2023.07.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371762/
https://www.ncbi.nlm.nih.gov/pubmed/37502679
http://dx.doi.org/10.1016/j.bioactmat.2023.07.010

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