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Complimentary electrostatics dominate T-cell receptor binding to a psoriasis-associated peptide antigen presented by human leukocyte antigen C∗06:02

Psoriasis is a chronic skin disease characterized by hyperproliferative epidermal lesions infiltrated by autoreactive T cells. Individuals expressing the human leukocyte antigen (HLA) C∗06:02 allele are at highest risk for developing psoriasis. An autoreactive T cell clone (termed Vα3S1/Vβ13S1) isol...

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Detalles Bibliográficos
Autores principales:	Anand, Sushma, Littler, Dene R., Mobbs, Jesse I., Braun, Asolina, Baker, Daniel G., Tennant, Luke, Purcell, Anthony W., Vivian, Julian P., Rossjohn, Jamie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371836/ https://www.ncbi.nlm.nih.gov/pubmed/37330172 http://dx.doi.org/10.1016/j.jbc.2023.104930

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