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Efficacy against pneumococcal carriage and the immunogenicity of reduced-dose (0 + 1 and 1 + 1) PCV10 and PCV13 schedules in Ho Chi Minh City, Viet Nam: a parallel, single-blind, randomised controlled trial

BACKGROUND: Interest in reduced-dose pneumococcal conjugate vaccine (PCV) schedules is growing, but data on their ability to provide direct and indirect protection are scarce. We evaluated 1 + 1 (at 2 months and 12 months) and 0 + 1 (at 12 months) schedules of PCV10 or PCV13 in a predominately unvac...

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Detalles Bibliográficos
Autores principales: Temple, Beth, Tran, Hau Phuc, Dai, Vo Thi Trang, Smith-Vaughan, Heidi, Licciardi, Paul Vincent, Satzke, Catherine, Nguyen, Thuong Vu, Mulholland, Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science ;, The Lancet Pub. Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371874/
https://www.ncbi.nlm.nih.gov/pubmed/37062304
http://dx.doi.org/10.1016/S1473-3099(23)00061-0