A ubiquitin-based effector-to-inhibitor switch coordinates early brain, craniofacial, and skin development

The molecular mechanisms that coordinate patterning of the embryonic ectoderm into spatially distinct lineages to form the nervous system, epidermis, and neural crest-derived craniofacial structures are unclear. Here, biochemical disease-variant profiling reveals a posttranslational pathway that dri...

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Detalles Bibliográficos
Autores principales: Asmar, Anthony J., Abrams, Shaun R., Hsin, Jenny, Collins, Jason C., Yazejian, Rita M., Wu, Youmei, Cho, Jean, Doyle, Andrew D., Cinthala, Samhitha, Simon, Marleen, van Jaarsveld, Richard H., Beck, David B., Kerosuo, Laura, Werner, Achim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371987/
https://www.ncbi.nlm.nih.gov/pubmed/37495603
http://dx.doi.org/10.1038/s41467-023-40223-y

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