High throughput human genotyping for variants associated with malarial disease outcomes using custom targeted amplicon sequencing

Malaria has exhibited the strongest known selective pressure on the human genome in recent history and is the evolutionary driving force behind genetic conditions, such as sickle-cell disease, glucose-6-phosphatase deficiency, and some other erythrocyte defects. Genomic studies (e.g., The 1000 Genom...

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Detalles Bibliográficos
Autores principales: Osborne, Ashley, Phelan, Jody E., Vanheer, Leen N., Manjurano, Alphaxard, Gitaka, Jesse, Drakeley, Christopher J., Kaneko, Akira, Kita, Kiyoshi, Campino, Susana, Clark, Taane G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371994/
https://www.ncbi.nlm.nih.gov/pubmed/37495620
http://dx.doi.org/10.1038/s41598-023-39233-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371994/
https://www.ncbi.nlm.nih.gov/pubmed/37495620
http://dx.doi.org/10.1038/s41598-023-39233-z

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