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Numerical investigation of the dynamics of a rigid spherical particle in a vortical cross-slot flow at moderate inertia
The study of flow and particle dynamics in microfluidic cross-slot channels is of high relevance for lab-on-a-chip applications. In this work, we investigate the dynamics of a rigid spherical particle in a cross-slot junction for a channel height-to-width ratio of 0.6 and at a Reynolds number of 120...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372015/ https://www.ncbi.nlm.nih.gov/pubmed/37519826 http://dx.doi.org/10.1038/s41378-023-00541-z |
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author | Kechagidis, Konstantinos Owen, Benjamin Guillou, Lionel Tse, Henry Di Carlo, Dino Krüger, Timm |
author_facet | Kechagidis, Konstantinos Owen, Benjamin Guillou, Lionel Tse, Henry Di Carlo, Dino Krüger, Timm |
author_sort | Kechagidis, Konstantinos |
collection | PubMed |
description | The study of flow and particle dynamics in microfluidic cross-slot channels is of high relevance for lab-on-a-chip applications. In this work, we investigate the dynamics of a rigid spherical particle in a cross-slot junction for a channel height-to-width ratio of 0.6 and at a Reynolds number of 120 for which a steady vortex exists in the junction area. Using an in-house immersed-boundary-lattice-Boltzmann code, we analyse the effect of the entry position of the particle in the junction and the particle size on the dynamics and trajectory shape of the particle. We find that the dynamics of the particle depend strongly on its lateral entry position in the junction and weakly on its vertical entry position; particles that enter close to the centre show trajectory oscillations. Larger particles have longer residence times in the junction and tend to oscillate less due to their confinement. Our work contributes to the understanding of particle dynamics in intersecting flows and enables the design of optimised geometries for cytometry and particle manipulation. [Image: see text] |
format | Online Article Text |
id | pubmed-10372015 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-103720152023-07-28 Numerical investigation of the dynamics of a rigid spherical particle in a vortical cross-slot flow at moderate inertia Kechagidis, Konstantinos Owen, Benjamin Guillou, Lionel Tse, Henry Di Carlo, Dino Krüger, Timm Microsyst Nanoeng Article The study of flow and particle dynamics in microfluidic cross-slot channels is of high relevance for lab-on-a-chip applications. In this work, we investigate the dynamics of a rigid spherical particle in a cross-slot junction for a channel height-to-width ratio of 0.6 and at a Reynolds number of 120 for which a steady vortex exists in the junction area. Using an in-house immersed-boundary-lattice-Boltzmann code, we analyse the effect of the entry position of the particle in the junction and the particle size on the dynamics and trajectory shape of the particle. We find that the dynamics of the particle depend strongly on its lateral entry position in the junction and weakly on its vertical entry position; particles that enter close to the centre show trajectory oscillations. Larger particles have longer residence times in the junction and tend to oscillate less due to their confinement. Our work contributes to the understanding of particle dynamics in intersecting flows and enables the design of optimised geometries for cytometry and particle manipulation. [Image: see text] Nature Publishing Group UK 2023-07-26 /pmc/articles/PMC10372015/ /pubmed/37519826 http://dx.doi.org/10.1038/s41378-023-00541-z Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Kechagidis, Konstantinos Owen, Benjamin Guillou, Lionel Tse, Henry Di Carlo, Dino Krüger, Timm Numerical investigation of the dynamics of a rigid spherical particle in a vortical cross-slot flow at moderate inertia |
title | Numerical investigation of the dynamics of a rigid spherical particle in a vortical cross-slot flow at moderate inertia |
title_full | Numerical investigation of the dynamics of a rigid spherical particle in a vortical cross-slot flow at moderate inertia |
title_fullStr | Numerical investigation of the dynamics of a rigid spherical particle in a vortical cross-slot flow at moderate inertia |
title_full_unstemmed | Numerical investigation of the dynamics of a rigid spherical particle in a vortical cross-slot flow at moderate inertia |
title_short | Numerical investigation of the dynamics of a rigid spherical particle in a vortical cross-slot flow at moderate inertia |
title_sort | numerical investigation of the dynamics of a rigid spherical particle in a vortical cross-slot flow at moderate inertia |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372015/ https://www.ncbi.nlm.nih.gov/pubmed/37519826 http://dx.doi.org/10.1038/s41378-023-00541-z |
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