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Influencing factors on morbidity and mortality in intertrochanteric fractures

We aimed to evaluate the effect of the patient’s clinical and paraclinical condition before and after surgery on short-term mortality and complication and long-term mortality. A retrospective cohort study was conducted and multivariate logistic regression was applied to determine the effect of demog...

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Autores principales: Babagoli, Mazyar, Ghaseminejad Raeini, Amirhossein, Sheykhvatan, Mehrdad, Baghdadi, Soroush, Shafiei, Seyyed Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372085/
https://www.ncbi.nlm.nih.gov/pubmed/37495718
http://dx.doi.org/10.1038/s41598-023-38667-9
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author Babagoli, Mazyar
Ghaseminejad Raeini, Amirhossein
Sheykhvatan, Mehrdad
Baghdadi, Soroush
Shafiei, Seyyed Hossein
author_facet Babagoli, Mazyar
Ghaseminejad Raeini, Amirhossein
Sheykhvatan, Mehrdad
Baghdadi, Soroush
Shafiei, Seyyed Hossein
author_sort Babagoli, Mazyar
collection PubMed
description We aimed to evaluate the effect of the patient’s clinical and paraclinical condition before and after surgery on short-term mortality and complication and long-term mortality. A retrospective cohort study was conducted and multivariate logistic regression was applied to determine the effect of demographic characteristics (sex, age, AO/OTA classification, height, weight, body mass index), medical history (hypertension, ischemic heart disease, diabetes mellitus, thyroid malfunction, cancer, osteoporosis, smoking) lab data (Complete blood cell, blood sugar, Blood Urea Nitrogen, Creatinine, Na, and K), surgery-related factors (Anesthesia time and type, implant, intraoperative blood transfusion, postoperative blood transfusion, and operation time), duration of admission to surgery and anticoagulant consumption on short-term mortality and complication and long-term mortality. Three hundred ten patients from November 2016 to September 2020 were diagnosed with an intertrochanteric fracture. 3.23% of patients died in hospital, 14.1% of patients confronted in-hospital complications, and 38.3% died after discharge till the study endpoint. ΔNumber of Neutrophiles is the primary determinant for in-hospital mortality in multivariate analysis. Age and blood transfusion are the main determinants of long-term mortality, and Na before surgery is the primary variable associated with postoperative complications. Among different analytical factors Na before surgery as a biomarker presenting dehydration was the main prognostic factor for in hospital complications. In hospital mortality was mainly because of infection and long-term mortality was associated with blood transfusion.
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spelling pubmed-103720852023-07-28 Influencing factors on morbidity and mortality in intertrochanteric fractures Babagoli, Mazyar Ghaseminejad Raeini, Amirhossein Sheykhvatan, Mehrdad Baghdadi, Soroush Shafiei, Seyyed Hossein Sci Rep Article We aimed to evaluate the effect of the patient’s clinical and paraclinical condition before and after surgery on short-term mortality and complication and long-term mortality. A retrospective cohort study was conducted and multivariate logistic regression was applied to determine the effect of demographic characteristics (sex, age, AO/OTA classification, height, weight, body mass index), medical history (hypertension, ischemic heart disease, diabetes mellitus, thyroid malfunction, cancer, osteoporosis, smoking) lab data (Complete blood cell, blood sugar, Blood Urea Nitrogen, Creatinine, Na, and K), surgery-related factors (Anesthesia time and type, implant, intraoperative blood transfusion, postoperative blood transfusion, and operation time), duration of admission to surgery and anticoagulant consumption on short-term mortality and complication and long-term mortality. Three hundred ten patients from November 2016 to September 2020 were diagnosed with an intertrochanteric fracture. 3.23% of patients died in hospital, 14.1% of patients confronted in-hospital complications, and 38.3% died after discharge till the study endpoint. ΔNumber of Neutrophiles is the primary determinant for in-hospital mortality in multivariate analysis. Age and blood transfusion are the main determinants of long-term mortality, and Na before surgery is the primary variable associated with postoperative complications. Among different analytical factors Na before surgery as a biomarker presenting dehydration was the main prognostic factor for in hospital complications. In hospital mortality was mainly because of infection and long-term mortality was associated with blood transfusion. Nature Publishing Group UK 2023-07-26 /pmc/articles/PMC10372085/ /pubmed/37495718 http://dx.doi.org/10.1038/s41598-023-38667-9 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Babagoli, Mazyar
Ghaseminejad Raeini, Amirhossein
Sheykhvatan, Mehrdad
Baghdadi, Soroush
Shafiei, Seyyed Hossein
Influencing factors on morbidity and mortality in intertrochanteric fractures
title Influencing factors on morbidity and mortality in intertrochanteric fractures
title_full Influencing factors on morbidity and mortality in intertrochanteric fractures
title_fullStr Influencing factors on morbidity and mortality in intertrochanteric fractures
title_full_unstemmed Influencing factors on morbidity and mortality in intertrochanteric fractures
title_short Influencing factors on morbidity and mortality in intertrochanteric fractures
title_sort influencing factors on morbidity and mortality in intertrochanteric fractures
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372085/
https://www.ncbi.nlm.nih.gov/pubmed/37495718
http://dx.doi.org/10.1038/s41598-023-38667-9
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