Antibody Fc-binding profiles and ACE2 affinity to SARS-CoV-2 RBD variants

Emerging SARS-CoV-2 variants, notably Omicron, continue to remain a formidable challenge to worldwide public health. The SARS-CoV-2 receptor-binding domain (RBD) is a hotspot for mutations, reflecting its critical role at the ACE2 interface during viral entry. Here, we comprehensively investigated t...

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Detalles Bibliográficos
Autores principales: Haycroft, Ebene R., Davis, Samantha K., Ramanathan, Pradhipa, Lopez, Ester, Purcell, Ruth A., Tan, Li Lynn, Pymm, Phillip, Wines, Bruce D., Hogarth, P. Mark, Wheatley, Adam K., Juno, Jennifer A., Redmond, Samuel J., Gherardin, Nicholas A., Godfrey, Dale I., Tham, Wai-Hong, Selva, Kevin John, Kent, Stephen J., Chung, Amy W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372118/
https://www.ncbi.nlm.nih.gov/pubmed/37477828
http://dx.doi.org/10.1007/s00430-023-00773-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372118/
https://www.ncbi.nlm.nih.gov/pubmed/37477828
http://dx.doi.org/10.1007/s00430-023-00773-w

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