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Integrative Bioinformatics Analysis of mRNA Expression Profiles of Mice to Explore the Key Genes Involved in Crim1 Mutation-Induced Congenital Cataracts

Crim1 has been implicated in cataracts in mice and is of great importance in the development of the eye in both humans and mice. Therefore, we aimed to clarify how Crim1 mutations affect lens development and the molecular mechanism of cataracts in mice through comprehensive bioinformatics analysis....

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Detalles Bibliográficos
Autores principales: Zhang, Ziran, Meng, Fanke, Zhou, Jing, Zhang, Zhihan, Liang, Xiaotian, Meng, Meijun, Yi, Guoguo, Fu, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372119/
https://www.ncbi.nlm.nih.gov/pubmed/36586009
http://dx.doi.org/10.1007/s10528-022-10323-3