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Integrative Bioinformatics Analysis of mRNA Expression Profiles of Mice to Explore the Key Genes Involved in Crim1 Mutation-Induced Congenital Cataracts
Crim1 has been implicated in cataracts in mice and is of great importance in the development of the eye in both humans and mice. Therefore, we aimed to clarify how Crim1 mutations affect lens development and the molecular mechanism of cataracts in mice through comprehensive bioinformatics analysis....
Autores principales: | Zhang, Ziran, Meng, Fanke, Zhou, Jing, Zhang, Zhihan, Liang, Xiaotian, Meng, Meijun, Yi, Guoguo, Fu, Min |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372119/ https://www.ncbi.nlm.nih.gov/pubmed/36586009 http://dx.doi.org/10.1007/s10528-022-10323-3 |
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