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Development of rat duodenal monolayer model with effective barrier function from rat organoids for ADME assay
The in-depth analysis of the ADME profiles of drug candidates using in vitro models is essential for drug development since a drug’s exposure in humans depends on its ADME properties. In contrast to efforts in developing human in vitro absorption models, only a limited number of studies have explore...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372144/ https://www.ncbi.nlm.nih.gov/pubmed/37495742 http://dx.doi.org/10.1038/s41598-023-39425-7 |