Cargando…
Retention and Predictors of Attrition Among People Living With HIV on Antiretroviral Therapy in Guinea: A 13-Year Historical Cohort Study in Nine Large-Volume Sites
Objectives: The objective of this study was to estimate the retention rate of patients in an ART program and identify the predictors of attrition. Methods: This was a historical cohort study of HIV patients who started ART between September 2007 and April 2020, and were followed up on for at least 6...
Autores principales: | , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372218/ https://www.ncbi.nlm.nih.gov/pubmed/37519433 http://dx.doi.org/10.3389/ijph.2023.1605929 |
_version_ | 1785078323275104256 |
---|---|
author | Leno, Niouma Nestor Guilavogui, Foromo Camara, Alioune Kadio, Kadio Jean-Jacques Olivier Guilavogui, Timothé Diallo, Thierno Saidou Diallo, Mamadou Aliou Leno, Daniel William Athanase Ricarte, Button Koita, Youssouf Kaba, Laye Ahiatsi, Arnold Touré, Nagnouman Traoré, Pascal Chaloub, Souleymane Kamano, André Vicente, Carlos Arias Delamou, Alexandre Cissé, Mohamed |
author_facet | Leno, Niouma Nestor Guilavogui, Foromo Camara, Alioune Kadio, Kadio Jean-Jacques Olivier Guilavogui, Timothé Diallo, Thierno Saidou Diallo, Mamadou Aliou Leno, Daniel William Athanase Ricarte, Button Koita, Youssouf Kaba, Laye Ahiatsi, Arnold Touré, Nagnouman Traoré, Pascal Chaloub, Souleymane Kamano, André Vicente, Carlos Arias Delamou, Alexandre Cissé, Mohamed |
author_sort | Leno, Niouma Nestor |
collection | PubMed |
description | Objectives: The objective of this study was to estimate the retention rate of patients in an ART program and identify the predictors of attrition. Methods: This was a historical cohort study of HIV patients who started ART between September 2007 and April 2020, and were followed up on for at least 6 months in nine large-volume sites. Kaplan Meier techniques were used to estimate cumulative retention and attrition probabilities. Cox proportional hazards models were used to identify predictors of attrition. Results: The cumulative probability of retention at 12 and 24 months was 76.2% and 70.2%, respectively. The attrition rate after a median follow-up time of 3.1 years was 35.2%, or an incidence of 11.4 per 100 person-years. Having initiated ART between 2012 and 2015; unmarried status; having initiated ART with CD4 count <100 cells/μL; and having initiated ART at an advanced clinical stage were factors significantly associated with attrition. Conclusion: The retention rate in our study is much lower than the proposed national target (90%). Studies to understand the reasons for loss to follow-up are needed. |
format | Online Article Text |
id | pubmed-10372218 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-103722182023-07-28 Retention and Predictors of Attrition Among People Living With HIV on Antiretroviral Therapy in Guinea: A 13-Year Historical Cohort Study in Nine Large-Volume Sites Leno, Niouma Nestor Guilavogui, Foromo Camara, Alioune Kadio, Kadio Jean-Jacques Olivier Guilavogui, Timothé Diallo, Thierno Saidou Diallo, Mamadou Aliou Leno, Daniel William Athanase Ricarte, Button Koita, Youssouf Kaba, Laye Ahiatsi, Arnold Touré, Nagnouman Traoré, Pascal Chaloub, Souleymane Kamano, André Vicente, Carlos Arias Delamou, Alexandre Cissé, Mohamed Int J Public Health Public Health Archive Objectives: The objective of this study was to estimate the retention rate of patients in an ART program and identify the predictors of attrition. Methods: This was a historical cohort study of HIV patients who started ART between September 2007 and April 2020, and were followed up on for at least 6 months in nine large-volume sites. Kaplan Meier techniques were used to estimate cumulative retention and attrition probabilities. Cox proportional hazards models were used to identify predictors of attrition. Results: The cumulative probability of retention at 12 and 24 months was 76.2% and 70.2%, respectively. The attrition rate after a median follow-up time of 3.1 years was 35.2%, or an incidence of 11.4 per 100 person-years. Having initiated ART between 2012 and 2015; unmarried status; having initiated ART with CD4 count <100 cells/μL; and having initiated ART at an advanced clinical stage were factors significantly associated with attrition. Conclusion: The retention rate in our study is much lower than the proposed national target (90%). Studies to understand the reasons for loss to follow-up are needed. Frontiers Media S.A. 2023-07-13 /pmc/articles/PMC10372218/ /pubmed/37519433 http://dx.doi.org/10.3389/ijph.2023.1605929 Text en Copyright © 2023 Leno, Guilavogui, Camara, Kadio, Guilavogui, Diallo, Diallo, Leno, Ricarte, Koita, Kaba, Ahiatsi, Touré, Traoré, Chaloub, Kamano, Vicente, Delamou and Cissé. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Public Health Archive Leno, Niouma Nestor Guilavogui, Foromo Camara, Alioune Kadio, Kadio Jean-Jacques Olivier Guilavogui, Timothé Diallo, Thierno Saidou Diallo, Mamadou Aliou Leno, Daniel William Athanase Ricarte, Button Koita, Youssouf Kaba, Laye Ahiatsi, Arnold Touré, Nagnouman Traoré, Pascal Chaloub, Souleymane Kamano, André Vicente, Carlos Arias Delamou, Alexandre Cissé, Mohamed Retention and Predictors of Attrition Among People Living With HIV on Antiretroviral Therapy in Guinea: A 13-Year Historical Cohort Study in Nine Large-Volume Sites |
title | Retention and Predictors of Attrition Among People Living With HIV on Antiretroviral Therapy in Guinea: A 13-Year Historical Cohort Study in Nine Large-Volume Sites |
title_full | Retention and Predictors of Attrition Among People Living With HIV on Antiretroviral Therapy in Guinea: A 13-Year Historical Cohort Study in Nine Large-Volume Sites |
title_fullStr | Retention and Predictors of Attrition Among People Living With HIV on Antiretroviral Therapy in Guinea: A 13-Year Historical Cohort Study in Nine Large-Volume Sites |
title_full_unstemmed | Retention and Predictors of Attrition Among People Living With HIV on Antiretroviral Therapy in Guinea: A 13-Year Historical Cohort Study in Nine Large-Volume Sites |
title_short | Retention and Predictors of Attrition Among People Living With HIV on Antiretroviral Therapy in Guinea: A 13-Year Historical Cohort Study in Nine Large-Volume Sites |
title_sort | retention and predictors of attrition among people living with hiv on antiretroviral therapy in guinea: a 13-year historical cohort study in nine large-volume sites |
topic | Public Health Archive |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372218/ https://www.ncbi.nlm.nih.gov/pubmed/37519433 http://dx.doi.org/10.3389/ijph.2023.1605929 |
work_keys_str_mv | AT lenonioumanestor retentionandpredictorsofattritionamongpeoplelivingwithhivonantiretroviraltherapyinguineaa13yearhistoricalcohortstudyinninelargevolumesites AT guilavoguiforomo retentionandpredictorsofattritionamongpeoplelivingwithhivonantiretroviraltherapyinguineaa13yearhistoricalcohortstudyinninelargevolumesites AT camaraalioune retentionandpredictorsofattritionamongpeoplelivingwithhivonantiretroviraltherapyinguineaa13yearhistoricalcohortstudyinninelargevolumesites AT kadiokadiojeanjacquesolivier retentionandpredictorsofattritionamongpeoplelivingwithhivonantiretroviraltherapyinguineaa13yearhistoricalcohortstudyinninelargevolumesites AT guilavoguitimothe retentionandpredictorsofattritionamongpeoplelivingwithhivonantiretroviraltherapyinguineaa13yearhistoricalcohortstudyinninelargevolumesites AT diallothiernosaidou retentionandpredictorsofattritionamongpeoplelivingwithhivonantiretroviraltherapyinguineaa13yearhistoricalcohortstudyinninelargevolumesites AT diallomamadoualiou retentionandpredictorsofattritionamongpeoplelivingwithhivonantiretroviraltherapyinguineaa13yearhistoricalcohortstudyinninelargevolumesites AT lenodanielwilliamathanase retentionandpredictorsofattritionamongpeoplelivingwithhivonantiretroviraltherapyinguineaa13yearhistoricalcohortstudyinninelargevolumesites AT ricartebutton retentionandpredictorsofattritionamongpeoplelivingwithhivonantiretroviraltherapyinguineaa13yearhistoricalcohortstudyinninelargevolumesites AT koitayoussouf retentionandpredictorsofattritionamongpeoplelivingwithhivonantiretroviraltherapyinguineaa13yearhistoricalcohortstudyinninelargevolumesites AT kabalaye retentionandpredictorsofattritionamongpeoplelivingwithhivonantiretroviraltherapyinguineaa13yearhistoricalcohortstudyinninelargevolumesites AT ahiatsiarnold retentionandpredictorsofattritionamongpeoplelivingwithhivonantiretroviraltherapyinguineaa13yearhistoricalcohortstudyinninelargevolumesites AT tourenagnouman retentionandpredictorsofattritionamongpeoplelivingwithhivonantiretroviraltherapyinguineaa13yearhistoricalcohortstudyinninelargevolumesites AT traorepascal retentionandpredictorsofattritionamongpeoplelivingwithhivonantiretroviraltherapyinguineaa13yearhistoricalcohortstudyinninelargevolumesites AT chaloubsouleymane retentionandpredictorsofattritionamongpeoplelivingwithhivonantiretroviraltherapyinguineaa13yearhistoricalcohortstudyinninelargevolumesites AT kamanoandre retentionandpredictorsofattritionamongpeoplelivingwithhivonantiretroviraltherapyinguineaa13yearhistoricalcohortstudyinninelargevolumesites AT vicentecarlosarias retentionandpredictorsofattritionamongpeoplelivingwithhivonantiretroviraltherapyinguineaa13yearhistoricalcohortstudyinninelargevolumesites AT delamoualexandre retentionandpredictorsofattritionamongpeoplelivingwithhivonantiretroviraltherapyinguineaa13yearhistoricalcohortstudyinninelargevolumesites AT cissemohamed retentionandpredictorsofattritionamongpeoplelivingwithhivonantiretroviraltherapyinguineaa13yearhistoricalcohortstudyinninelargevolumesites |