Susceptibility to adriamycin-induced hepatotoxicity in mice depends on PRKDC polymorphism

Adriamycin (ADR) is an effective chemotherapy drug for various cancers but has serious side effects. ADR-induced liver damage is a common problem during therapy, but the underlying mechanism remains to be fully understood. In contrast, ADR-induced glomerular damage is well studied in rodents, and se...

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Detalles Bibliográficos
Autores principales: WATANABE, Masaki, KAKUTANI, Momoka, ANDO, Ryo, HIURA, Koki, SASAKI, Hayato, OKAMURA, Tadashi, SASAKI, Nobuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2023
Materias:
Laboratory Animal Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372250/
https://www.ncbi.nlm.nih.gov/pubmed/37245991
http://dx.doi.org/10.1292/jvms.23-0115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372250/
https://www.ncbi.nlm.nih.gov/pubmed/37245991
http://dx.doi.org/10.1292/jvms.23-0115

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