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Susceptibility to adriamycin-induced hepatotoxicity in mice depends on PRKDC polymorphism
Adriamycin (ADR) is an effective chemotherapy drug for various cancers but has serious side effects. ADR-induced liver damage is a common problem during therapy, but the underlying mechanism remains to be fully understood. In contrast, ADR-induced glomerular damage is well studied in rodents, and se...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Japanese Society of Veterinary Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372250/ https://www.ncbi.nlm.nih.gov/pubmed/37245991 http://dx.doi.org/10.1292/jvms.23-0115 |