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Type II Cryoglobulinemic Membranoproliferative Glomerulonephritis Caused by Mucosa-associated Lymphoid Tissue Lymphoma
A 67-year-old man complained of lower limb edema with a purpuric skin rash. Laboratory tests revealed proteinuria, elevated serum creatinine levels, and low serum albumin levels. The patient was also positive for cryoglobulin in serum, immunoglobulin (Ig) M gammopathy, hypocomplementemia, and rheuma...
| Autores principales: | , , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Japanese Society of Internal Medicine
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372288/ https://www.ncbi.nlm.nih.gov/pubmed/37394661 http://dx.doi.org/10.2169/internalmedicine.0756-22 |
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| author | Sugihara, Ayano Ureshino, Hiroshi Yamasaki, Masatora Fukuda, Makoto Yoshihara, Maki Nonaka, Eriko Miyazaki, Mariko Fujita, Mai Ishii, Keitaro Kamachi, Kazuharu Sano, Haruhiko Okamoto, Sho Itamura, Hidekazu Yoshimura, Mariko Katsuya, Hiroo Ando, Toshihiko Aoki, Shigehisa Ubara, Yoshifumi Kimura, Shinya |
| author_facet | Sugihara, Ayano Ureshino, Hiroshi Yamasaki, Masatora Fukuda, Makoto Yoshihara, Maki Nonaka, Eriko Miyazaki, Mariko Fujita, Mai Ishii, Keitaro Kamachi, Kazuharu Sano, Haruhiko Okamoto, Sho Itamura, Hidekazu Yoshimura, Mariko Katsuya, Hiroo Ando, Toshihiko Aoki, Shigehisa Ubara, Yoshifumi Kimura, Shinya |
| author_sort | Sugihara, Ayano |
| collection | PubMed |
| description | A 67-year-old man complained of lower limb edema with a purpuric skin rash. Laboratory tests revealed proteinuria, elevated serum creatinine levels, and low serum albumin levels. The patient was also positive for cryoglobulin in serum, immunoglobulin (Ig) M gammopathy, hypocomplementemia, and rheumatoid factor. He was negative for anti-hepatitis C virus antibodies. A pathological analysis of the renal tissue revealed membranoproliferative glomerulonephritis, common histological features of cryoglobulinemic vasculitis (CV), and mucosa-associated lymphoid tissue lymphoma invasion. Although hematologic malignancy is a rare cause of type II CV, these clinical findings suggest that mucosa-associated lymphoid tissue lymphoma (MALT) lymphoma may have been the cause in the present case. |
| format | Online Article Text |
| id | pubmed-10372288 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2023 |
| publisher | The Japanese Society of Internal Medicine |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-103722882023-07-28 Type II Cryoglobulinemic Membranoproliferative Glomerulonephritis Caused by Mucosa-associated Lymphoid Tissue Lymphoma Sugihara, Ayano Ureshino, Hiroshi Yamasaki, Masatora Fukuda, Makoto Yoshihara, Maki Nonaka, Eriko Miyazaki, Mariko Fujita, Mai Ishii, Keitaro Kamachi, Kazuharu Sano, Haruhiko Okamoto, Sho Itamura, Hidekazu Yoshimura, Mariko Katsuya, Hiroo Ando, Toshihiko Aoki, Shigehisa Ubara, Yoshifumi Kimura, Shinya Intern Med Case Report A 67-year-old man complained of lower limb edema with a purpuric skin rash. Laboratory tests revealed proteinuria, elevated serum creatinine levels, and low serum albumin levels. The patient was also positive for cryoglobulin in serum, immunoglobulin (Ig) M gammopathy, hypocomplementemia, and rheumatoid factor. He was negative for anti-hepatitis C virus antibodies. A pathological analysis of the renal tissue revealed membranoproliferative glomerulonephritis, common histological features of cryoglobulinemic vasculitis (CV), and mucosa-associated lymphoid tissue lymphoma invasion. Although hematologic malignancy is a rare cause of type II CV, these clinical findings suggest that mucosa-associated lymphoid tissue lymphoma (MALT) lymphoma may have been the cause in the present case. The Japanese Society of Internal Medicine 2023-07-01 2023-07-01 /pmc/articles/PMC10372288/ /pubmed/37394661 http://dx.doi.org/10.2169/internalmedicine.0756-22 Text en Copyright © 2023 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/). |
| spellingShingle | Case Report Sugihara, Ayano Ureshino, Hiroshi Yamasaki, Masatora Fukuda, Makoto Yoshihara, Maki Nonaka, Eriko Miyazaki, Mariko Fujita, Mai Ishii, Keitaro Kamachi, Kazuharu Sano, Haruhiko Okamoto, Sho Itamura, Hidekazu Yoshimura, Mariko Katsuya, Hiroo Ando, Toshihiko Aoki, Shigehisa Ubara, Yoshifumi Kimura, Shinya Type II Cryoglobulinemic Membranoproliferative Glomerulonephritis Caused by Mucosa-associated Lymphoid Tissue Lymphoma |
| title | Type II Cryoglobulinemic Membranoproliferative Glomerulonephritis Caused by Mucosa-associated Lymphoid Tissue Lymphoma |
| title_full | Type II Cryoglobulinemic Membranoproliferative Glomerulonephritis Caused by Mucosa-associated Lymphoid Tissue Lymphoma |
| title_fullStr | Type II Cryoglobulinemic Membranoproliferative Glomerulonephritis Caused by Mucosa-associated Lymphoid Tissue Lymphoma |
| title_full_unstemmed | Type II Cryoglobulinemic Membranoproliferative Glomerulonephritis Caused by Mucosa-associated Lymphoid Tissue Lymphoma |
| title_short | Type II Cryoglobulinemic Membranoproliferative Glomerulonephritis Caused by Mucosa-associated Lymphoid Tissue Lymphoma |
| title_sort | type ii cryoglobulinemic membranoproliferative glomerulonephritis caused by mucosa-associated lymphoid tissue lymphoma |
| topic | Case Report |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372288/ https://www.ncbi.nlm.nih.gov/pubmed/37394661 http://dx.doi.org/10.2169/internalmedicine.0756-22 |
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