Maternal hyperglycemia induces alterations in hepatic amino acid, glucose and lipid metabolism of neonatal offspring: Multi-omics insights from a diabetic pig model

OBJECTIVE: To gain mechanistic insights into adverse effects of maternal hyperglycemia on the liver of neonates, we performed a multi-omics analysis of liver tissue from piglets developed in genetically diabetic (mutant INS gene induced diabetes of youth; MIDY) or wild-type (WT) pigs. METHODS: Prote...

Descripción completa

Detalles Bibliográficos
Autores principales: Shashikadze, Bachuki, Valla, Libera, Lombardo, Salvo Danilo, Prehn, Cornelia, Haid, Mark, Riols, Fabien, Stöckl, Jan Bernd, Elkhateib, Radwa, Renner, Simone, Rathkolb, Birgit, Menche, Jörg, Hrabĕ de Angelis, Martin, Wolf, Eckhard, Kemter, Elisabeth, Fröhlich, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372374/
https://www.ncbi.nlm.nih.gov/pubmed/37414142
http://dx.doi.org/10.1016/j.molmet.2023.101768

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372374/
https://www.ncbi.nlm.nih.gov/pubmed/37414142
http://dx.doi.org/10.1016/j.molmet.2023.101768

Ejemplares similares