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Weight increase in people with cystic fibrosis on CFTR modulator therapy is mainly due to increase in fat mass
Background: Ivacaftor, the first CFTR modulator drug, leads to significant long-term improvement in lung function and weight gain. The mechanism as well as the long-term impact of ivacaftor on weight, resting energy expenditure (REE) and body composition remains to be explored. Methods: This prospec...
Autores principales: | Mouzaki, Marialena, Dupuis, Annie, Avolio, Julie, Griffin, Katherine, Ratjen, Felix, Tullis, Elizabeth, Gonska, Tanja |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372433/ https://www.ncbi.nlm.nih.gov/pubmed/37521467 http://dx.doi.org/10.3389/fphar.2023.1157459 |
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