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Dissecting the role of the NADPH oxidase NOX4 in TGF-beta signaling in hepatocellular carcinoma

The NADPH oxidase NOX4 has been proposed as necessary for the apoptosis induced by the Transforming Growth Factor-beta (TGF-β) in hepatocytes and hepatocellular carcinoma (HCC) cells. However, whether NOX4 is required for TGF-β-induced canonical (SMADs) or non-canonical signals is not fully understo...

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Detalles Bibliográficos
Autores principales: Espinosa-Sotelo, Rut, Fusté, Noel P., Peñuelas-Haro, Irene, Alay, Ania, Pons, Gabriel, Almodóvar, Xènia, Albaladejo, Júlia, Sánchez-Vera, Ismael, Bonilla-Amadeo, Ricard, Dituri, Francesco, Serino, Grazia, Ramos, Emilio, Serrano, Teresa, Calvo, Mariona, Martínez-Chantar, María Luz, Giannelli, Gianluigi, Bertran, Esther, Fabregat, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372458/
https://www.ncbi.nlm.nih.gov/pubmed/37463530
http://dx.doi.org/10.1016/j.redox.2023.102818

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