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A Randomized Phase II Study of Irinotecan Plus Cisplatin with or without Simvastatin in Ever-Smokers with Extended Disease Small Cell Lung Cancer

PURPOSE: This study evaluated whether an addition of simvastatin to chemotherapy improves survival in ever-smokers with extensive disease (ED)–small cell lung cancer (SCLC). MATERIALS AND METHODS: This is an open-label randomized phase II study conducted in National Cancer Center (Goyang, Korea). Ch...

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Detalles Bibliográficos
Autores principales: Lee, Youngjoo, Lee, Soo-Hyun, Lee, Geon Kook, Lim, Eun Jin, Han, Ji-Youn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Cancer Association 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372610/
https://www.ncbi.nlm.nih.gov/pubmed/36960628
http://dx.doi.org/10.4143/crt.2023.283