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Anti–PD-L1 Antibody and/or 17β-Estradiol Treatment Induces Changes in the Gut Microbiome in MC38 Colon Tumor Model

PURPOSE: 17β-Estradiol (E2) supplementation suppresses MC38 tumor growth by downregulating the expression of programmed death-ligand 1 (PD-L1). This study aims to figure out the gut microbiota that respond to anti–PD-L1 and/or estrogen treatment in MC38 colon cancer model. MATERIALS AND METHODS: A s...

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Detalles Bibliográficos
Autores principales: Song, Chin-Hee, Kim, Nayoung, Nam, Ryoung Hee, Choi, Soo In, Jang, Jae Young, Choi, Jina, Lee, Ha-Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Cancer Association 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372611/
https://www.ncbi.nlm.nih.gov/pubmed/36634616
http://dx.doi.org/10.4143/crt.2022.1427