Proxalutamide reduces SARS-CoV-2 infection and associated inflammatory response

Early in the COVID-19 pandemic, data suggested that males had a higher risk of developing severe disease and that androgen deprivation therapy might be associated with protection. Combined with the fact that TMPRSS2 (transmembrane serine protease 2), a host entry factor for the SARS-CoV-2 virus, was...

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Detalles Bibliográficos
Autores principales: Qiao, Yuanyuan, Wotring, Jesse W., Zheng, Yang, Zhang, Charles J., Zhang, Yuping, Jiang, Xia, Pretto, Carla D., Eyunni, Sanjana, Parolia, Abhijit, He, Tongchen, Cheng, Caleb, Cao, Xuhong, Wang, Rui, Su, Fengyun, Ellison, Stephanie J., Wang, Yini, Qin, Jun, Yan, Honghua, Zhou, Qianxiang, Ma, Liandong, Sexton, Jonathan Z., Chinnaiyan, Arul M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372636/
https://www.ncbi.nlm.nih.gov/pubmed/37459541
http://dx.doi.org/10.1073/pnas.2221809120

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