The anti-inflammatory and anti-oxidative effect of a classical hypnotic bromovalerylurea mediated by the activation of NRF2

The Kelch-like ECH-associated protein 1–nuclear factor erythroid 2-related factor 2 (KEAP1–NRF2) system plays a central role in redox homeostasis and inflammation control. Oxidative stress or electrophilic compounds promote NRF2 stabilization and transcriptional activity by negatively regulating its...

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Detalles Bibliográficos
Autores principales: Takeda, Haruna, Nakajima, Yoshihiro, Yamaguchi, Teruaki, Watanabe, Itaru, Miyoshi, Shoko, Nagashio, Kodai, Sekine, Hiroki, Motohashi, Hozumi, Yano, Hajime, Tanaka, Junya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Regular Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372716/
https://www.ncbi.nlm.nih.gov/pubmed/37039781
http://dx.doi.org/10.1093/jb/mvad030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372716/
https://www.ncbi.nlm.nih.gov/pubmed/37039781
http://dx.doi.org/10.1093/jb/mvad030

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