A role for microsomal glutathione transferase 1 in melanin biosynthesis and melanoma progression

Recent advancements in the treatment of melanoma are encouraging, but there remains a need to identify additional therapeutic targets. We identify a role for microsomal glutathione transferase 1 (MGST1) in biosynthetic pathways for melanin and as a determinant of tumor progression. Knockdown (KD) of...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Jie, Ye, Zhi-wei, Bräutigam, Lars, Chakraborty, Paramita, Luo, Zhenwu, Culpepper, John, Aslam, Muhammad, Zhang, Leilei, Johansson, Katarina, Haeggström, Jesper Z., Xu, Jianqiang, Olsson, Magnus, Townsend, Danyelle M., Mehrotra, Shikhar, Morgenstern, Ralf, Tew, Kenneth D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372821/
https://www.ncbi.nlm.nih.gov/pubmed/37321450
http://dx.doi.org/10.1016/j.jbc.2023.104920

Ejemplares similares

Ejemplares similares