Activation of insulin-like growth factor-1 receptor (IGF-1R) promotes growth of colorectal cancer through triggering the MEX3A-mediated degradation of RIG-I

Insulin-like growth factor-1 receptor (IGF-1R) has been made an attractive anticancer target due to its overexpression in cancers. However, targeting it has often produced the disappointing results as the role played by cross talk with numerous downstream signalings. Here, we report a disobliging IG...

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Detalles Bibliográficos
Autores principales: Xie, Qiaobo, Chu, Yanyan, Yuan, Wenmin, Li, Yanan, Li, Keqin, Wu, Xinfeng, Liu, Xiaohui, Xu, Rui, Cui, Shuxiang, Qu, Xianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372823/
https://www.ncbi.nlm.nih.gov/pubmed/37521868
http://dx.doi.org/10.1016/j.apsb.2023.04.001

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