A redox-responsive self-assembling COA-4-arm PEG prodrug nanosystem for dual drug delivery suppresses cancer metastasis and drug resistance by downregulating hsp90 expression

Metastasis and resistance are main causes to affect the outcome of the current anticancer therapies. Heat shock protein 90 (Hsp90) as an ATP-dependent molecular chaperone takes important role in the tumor metastasis and resistance. Targeting Hsp90 and downregulating its expression show promising in...

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Detalles Bibliográficos
Autores principales: Zhou, Yi, Miao, Yingling, Huang, Qiudi, Shi, Wenwen, Xie, Jiacui, Lin, Jiachang, Huang, Pei, Yue, Chengfeng, Qin, Yuan, Yu, Xiyong, Wang, He, Qin, Linghao, Chen, Jianhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372829/
https://www.ncbi.nlm.nih.gov/pubmed/37521875
http://dx.doi.org/10.1016/j.apsb.2022.11.024

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