Insulin-Like Growth Factor1 Preserves Gastric Pacemaker Cells and Motor Function in Aging via ERK1/2 Activation

BACKGROUND & AIMS: Impaired gastric motor function in the elderly causes reduced food intake leading to frailty and sarcopenia. We previously found that aging-related impaired gastric compliance was mainly owing to depletion of interstitial cells of Cajal (ICC), pacemaker cells, and neuromodulat...

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Detalles Bibliográficos
Autores principales: Truong Thuy Nguyen, Vy, Taheri, Negar, Choi, Egan L., Kellogg, Todd A., Linden, David R., Hayashi, Yujiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372898/
https://www.ncbi.nlm.nih.gov/pubmed/37301443
http://dx.doi.org/10.1016/j.jcmgh.2023.06.002

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