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Hyperhomocysteinemia potentiates megakaryocyte differentiation and thrombopoiesis via GH-PI3K-Akt axis
Hyperhomocysteinemia (HHcy) is closely associated with thrombotic diseases such as myocardial infarction and stroke. Enhanced platelet activation was observed in animals and humans with HHcy. However, the influence of HHcy on thrombopoiesis remains largely unknown. Here, we reported increased platel...
Autores principales: | Lei, Wenjing, Liu, Zhuoliang, Su, Zhiyuan, Meng, Panpan, Zhou, Chun, Chen, Xiaomei, Hu, Zheng, Xiao, An, Zhou, Miaomiao, Huang, Liping, Zhang, Yiyue, Qin, Xianhui, Wang, Junping, Zhu, Fengxin, Nie, Jing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373258/ https://www.ncbi.nlm.nih.gov/pubmed/37501059 http://dx.doi.org/10.1186/s13045-023-01481-x |
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