Development of a robust induced pluripotent stem cell atrial cardiomyocyte differentiation protocol to model atrial arrhythmia

BACKGROUND: Atrial fibrillation is the most common arrhythmia syndrome and causes significant morbidity and mortality. Current therapeutics, however, have limited efficacy. Notably, many therapeutics shown to be efficacious in animal models have not proved effective in humans. Thus, there is a need...

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Detalles Bibliográficos
Autores principales: Thorpe, Jordan, Perry, Matthew D., Contreras, Osvaldo, Hurley, Emily, Parker, George, Harvey, Richard P., Hill, Adam P., Vandenberg, Jamie I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373292/
https://www.ncbi.nlm.nih.gov/pubmed/37501071
http://dx.doi.org/10.1186/s13287-023-03405-5

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