Designing Potent α-Glucosidase Inhibitors: A Synthesis and QSAR Modeling Approach for Biscoumarin Derivatives

[Image: see text] Nineteen biscoumarins were synthesized, well-characterized, and evaluated against α-glucosidases in vitro. Of these, six compounds (10, 12, 16, and 17–19) were newly synthesized and not previously reported in the chemical literature. The majority of the synthesized derivatives demo...

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Detalles Bibliográficos
Autores principales: Phan, Thi-Hong-Truc, Hengphasatporn, Kowit, Shigeta, Yasuteru, Xie, Wanting, Maitarad, Phornphimon, Rungrotmongkol, Thanyada, Chavasiri, Warinthorn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373460/
https://www.ncbi.nlm.nih.gov/pubmed/37521599
http://dx.doi.org/10.1021/acsomega.3c02868

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373460/
https://www.ncbi.nlm.nih.gov/pubmed/37521599
http://dx.doi.org/10.1021/acsomega.3c02868

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