Cargando…

Designing Potent α-Glucosidase Inhibitors: A Synthesis and QSAR Modeling Approach for Biscoumarin Derivatives

[Image: see text] Nineteen biscoumarins were synthesized, well-characterized, and evaluated against α-glucosidases in vitro. Of these, six compounds (10, 12, 16, and 17–19) were newly synthesized and not previously reported in the chemical literature. The majority of the synthesized derivatives demo...

Descripción completa

Detalles Bibliográficos
Autores principales: Phan, Thi-Hong-Truc, Hengphasatporn, Kowit, Shigeta, Yasuteru, Xie, Wanting, Maitarad, Phornphimon, Rungrotmongkol, Thanyada, Chavasiri, Warinthorn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373460/
https://www.ncbi.nlm.nih.gov/pubmed/37521599
http://dx.doi.org/10.1021/acsomega.3c02868

Ejemplares similares