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SLF2 Interacts with the SMC5/6 Complex to Direct Hepatitis B Virus Episomal DNA to Promyelocytic Leukemia Bodies for Transcriptional Repression

Hepatitis B virus (HBV) chronically infects approximately 300 million people worldwide, and permanently repressing transcription of covalently closed circular DNA (cccDNA), the episomal viral DNA reservoir, is an attractive approach toward curing HBV. However, the mechanism underlying cccDNA transcr...

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Detalles Bibliográficos
Autores principales: Yao, Qiyan, Peng, Bo, Li, Cong, Li, Xuelei, Chen, Mingyi, Zhou, Zhongmin, Tang, Dingbin, He, Jiabei, Wu, Yumeng, Sun, Yinyan, Li, Wenhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373549/
https://www.ncbi.nlm.nih.gov/pubmed/37338350
http://dx.doi.org/10.1128/jvi.00328-23

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