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Pattern recognition receptor agonists in pathogen vaccines mediate antitumor T-cell cross-priming

BACKGROUND: Cancer immunotherapies are generally effective in patients whose tumors contain a priori primed T-cells reactive to tumor antigens (TA). One approach to prime TA-reactive T-cells is to administer immunostimulatory molecules, cells, or pathogens directly to the tumor site, that is, in sit...

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Detalles Bibliográficos
Autores principales:	Aleynick, Mark, Svensson-Arvelund, Judit, Pantsulaia, Gvantsa, Kim, Kristy, Rose, Samuel A, Upadhyay, Ranjan, Yellin, Michael, Marsh, Henry, Oreper, Daniel, Jhunjhunwala, Suchit, Moussion, Christine Carine, Merad, Miriam, Brown, Brian D, Brody, Joshua D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2023
Materias:	Oncolytic and Local Immunotherapy
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373699/ https://www.ncbi.nlm.nih.gov/pubmed/37487664 http://dx.doi.org/10.1136/jitc-2023-007198

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