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Reproducible generation of human retinal ganglion cells from banked retinal progenitor cells: analysis of target recognition and IGF-1-mediated axon regeneration

The selective degeneration of retinal ganglion cells (RGCs) is a common feature in glaucoma, a complex group of diseases, leading to irreversible vision loss. Stem cell-based glaucoma disease modeling, cell replacement, and axon regeneration are viable approaches to understand mechanisms underlying...

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Detalles Bibliográficos
Autores principales: Subramani, Murali, Van Hook, Matthew J., Ahmad, Iqbal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373790/
https://www.ncbi.nlm.nih.gov/pubmed/37519299
http://dx.doi.org/10.3389/fcell.2023.1214104