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Nanodrugs systems for therapy and diagnosis of esophageal cancer
With the increasing incidence of esophageal cancer, its diagnosis and treatment have become one of the key issues in medical research today. However, the current diagnostic and treatment methods face many unresolved issues, such as low accuracy of early diagnosis, painful treatment process for patie...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373894/ https://www.ncbi.nlm.nih.gov/pubmed/37520291 http://dx.doi.org/10.3389/fbioe.2023.1233476 |
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author | Zhang, Lihan Li, Xing Yue, Guangxing Guo, Lihao Hu, Yanhui Cui, Qingli Wang, Jia Tang, Jingwen Liu, Huaimin |
author_facet | Zhang, Lihan Li, Xing Yue, Guangxing Guo, Lihao Hu, Yanhui Cui, Qingli Wang, Jia Tang, Jingwen Liu, Huaimin |
author_sort | Zhang, Lihan |
collection | PubMed |
description | With the increasing incidence of esophageal cancer, its diagnosis and treatment have become one of the key issues in medical research today. However, the current diagnostic and treatment methods face many unresolved issues, such as low accuracy of early diagnosis, painful treatment process for patients, and high recurrence rate after recovery. Therefore, new methods for the diagnosis and treatment of esophageal cancer need to be further explored, and the rapid development of nanomaterials has brought new ideas for solving this problem. Nanomaterials used as drugs or drug delivery systems possess several advantages, such as high drug capacity, adjustably specific targeting capability, and stable structure, which endow nanomaterials great application potential in cancer therapy. However, even though the nanomaterials have been widely used in cancer therapy, there are still few reviews on their application in esophageal cancer, and systematical overview and analysis are deficient. Herein, we overviewed the application of nanodrug systems in therapy and diagnosis of esophageal cancer and summarized some representative case of their application in diagnosis, chemotherapy, targeted drug, radiotherapy, immunity, surgery and new therapeutic method of esophageal cancer. In addition, the nanomaterials used for therapy of esophageal cancer complications, esophageal stenosis or obstruction and oesophagitis, are also listed here. Finally, the challenge and the future of nanomaterials used in cancer therapy were discussed. |
format | Online Article Text |
id | pubmed-10373894 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-103738942023-07-28 Nanodrugs systems for therapy and diagnosis of esophageal cancer Zhang, Lihan Li, Xing Yue, Guangxing Guo, Lihao Hu, Yanhui Cui, Qingli Wang, Jia Tang, Jingwen Liu, Huaimin Front Bioeng Biotechnol Bioengineering and Biotechnology With the increasing incidence of esophageal cancer, its diagnosis and treatment have become one of the key issues in medical research today. However, the current diagnostic and treatment methods face many unresolved issues, such as low accuracy of early diagnosis, painful treatment process for patients, and high recurrence rate after recovery. Therefore, new methods for the diagnosis and treatment of esophageal cancer need to be further explored, and the rapid development of nanomaterials has brought new ideas for solving this problem. Nanomaterials used as drugs or drug delivery systems possess several advantages, such as high drug capacity, adjustably specific targeting capability, and stable structure, which endow nanomaterials great application potential in cancer therapy. However, even though the nanomaterials have been widely used in cancer therapy, there are still few reviews on their application in esophageal cancer, and systematical overview and analysis are deficient. Herein, we overviewed the application of nanodrug systems in therapy and diagnosis of esophageal cancer and summarized some representative case of their application in diagnosis, chemotherapy, targeted drug, radiotherapy, immunity, surgery and new therapeutic method of esophageal cancer. In addition, the nanomaterials used for therapy of esophageal cancer complications, esophageal stenosis or obstruction and oesophagitis, are also listed here. Finally, the challenge and the future of nanomaterials used in cancer therapy were discussed. Frontiers Media S.A. 2023-07-13 /pmc/articles/PMC10373894/ /pubmed/37520291 http://dx.doi.org/10.3389/fbioe.2023.1233476 Text en Copyright © 2023 Zhang, Li, Yue, Guo, Hu, Cui, Wang, Tang and Liu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Bioengineering and Biotechnology Zhang, Lihan Li, Xing Yue, Guangxing Guo, Lihao Hu, Yanhui Cui, Qingli Wang, Jia Tang, Jingwen Liu, Huaimin Nanodrugs systems for therapy and diagnosis of esophageal cancer |
title | Nanodrugs systems for therapy and diagnosis of esophageal cancer |
title_full | Nanodrugs systems for therapy and diagnosis of esophageal cancer |
title_fullStr | Nanodrugs systems for therapy and diagnosis of esophageal cancer |
title_full_unstemmed | Nanodrugs systems for therapy and diagnosis of esophageal cancer |
title_short | Nanodrugs systems for therapy and diagnosis of esophageal cancer |
title_sort | nanodrugs systems for therapy and diagnosis of esophageal cancer |
topic | Bioengineering and Biotechnology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373894/ https://www.ncbi.nlm.nih.gov/pubmed/37520291 http://dx.doi.org/10.3389/fbioe.2023.1233476 |
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