NRF2 activators inhibit influenza A virus replication by interfering with nucleo-cytoplasmic export of viral RNPs in an NRF2-independent manner

In addition to antioxidative and anti-inflammatory properties, activators of the cytoprotective nuclear factor erythroid-2-like-2 (NRF2) signaling pathway have antiviral effects, but the underlying antiviral mechanisms are incompletely understood. We evaluated the ability of the NRF2 activators 4-oc...

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Detalles Bibliográficos
Autores principales: Waqas, Fakhar H., Shehata, Mahmoud, Elgaher, Walid A. M., Lacour, Antoine, Kurmasheva, Naziia, Begnini, Fabio, Kiib, Anders E., Dahlmann, Julia, Chen, Chutao, Pavlou, Andreas, Poulsen, Thomas B., Merkert, Sylvia, Martin, Ulrich, Olmer, Ruth, Olagnier, David, Hirsch, Anna K. H., Pleschka, Stephan, Pessler, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374058/
https://www.ncbi.nlm.nih.gov/pubmed/37459366
http://dx.doi.org/10.1371/journal.ppat.1011506

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