MAVS Antagonizes Human Stem Cell Senescence as a Mitochondrial Stabilizer

Mitochondrial dysfunction is a hallmark feature of cellular senescence and organ aging. Here, we asked whether the mitochondrial antiviral signaling protein (MAVS), which is essential for driving antiviral response, also regulates human stem cell senescence. To answer this question, we used CRISPR/C...

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Detalles Bibliográficos
Autores principales: Wang, Cui, Yang, Kuan, Liu, Xiaoqian, Wang, Si, Song, Moshi, Belmonte, Juan Carlos Izpisua, Qu, Jing, Liu, Guang-Hui, Zhang, Weiqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAAS 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374246/
https://www.ncbi.nlm.nih.gov/pubmed/37521327
http://dx.doi.org/10.34133/research.0192

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