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Biosynthesized nanoparticles: a novel approach for cancer therapeutics

Nanotechnology has become one of the most rapid, innovative, and adaptable sciences in modern science and cancer therapy. Traditional chemotherapy has limits owing to its non-specific nature and adverse side effects on healthy cells, and it remains a serious worldwide health issue. Because of their...

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Autores principales: Chaturvedi, Vivek K., Sharma, Bhaskar, Tripathi, Abhay Dev, Yadav, Dawesh P., Singh, Kshitij RB, Singh, Jay, Singh, Ravindra Pratap
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374256/
https://www.ncbi.nlm.nih.gov/pubmed/37521721
http://dx.doi.org/10.3389/fmedt.2023.1236107
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author Chaturvedi, Vivek K.
Sharma, Bhaskar
Tripathi, Abhay Dev
Yadav, Dawesh P.
Singh, Kshitij RB
Singh, Jay
Singh, Ravindra Pratap
author_facet Chaturvedi, Vivek K.
Sharma, Bhaskar
Tripathi, Abhay Dev
Yadav, Dawesh P.
Singh, Kshitij RB
Singh, Jay
Singh, Ravindra Pratap
author_sort Chaturvedi, Vivek K.
collection PubMed
description Nanotechnology has become one of the most rapid, innovative, and adaptable sciences in modern science and cancer therapy. Traditional chemotherapy has limits owing to its non-specific nature and adverse side effects on healthy cells, and it remains a serious worldwide health issue. Because of their capacity to specifically target cancer cells and deliver therapeutic chemicals directly to them, nanoparticles have emerged as a viable strategy for cancer therapies. Nanomaterials disclose novel properties based on size, distribution, and shape. Biosynthesized or biogenic nanoparticles are a novel technique with anti-cancer capabilities, such as triggering apoptosis in cancer cells and slowing tumour growth. They may be configured to deliver medications or other therapies to specific cancer cells or tumour markers. Despite their potential, biosynthesized nanoparticles confront development obstacles such as a lack of standardisation in their synthesis and characterization, the possibility of toxicity, and their efficiency against various forms of cancer. The effectiveness and safety of biosynthesized nanoparticles must be further investigated, as well as the types of cancer they are most successful against. This review discusses the promise of biosynthesized nanoparticles as a novel approach for cancer therapeutics, as well as their mode of action and present barriers to their development.
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spelling pubmed-103742562023-07-28 Biosynthesized nanoparticles: a novel approach for cancer therapeutics Chaturvedi, Vivek K. Sharma, Bhaskar Tripathi, Abhay Dev Yadav, Dawesh P. Singh, Kshitij RB Singh, Jay Singh, Ravindra Pratap Front Med Technol Medical Technology Nanotechnology has become one of the most rapid, innovative, and adaptable sciences in modern science and cancer therapy. Traditional chemotherapy has limits owing to its non-specific nature and adverse side effects on healthy cells, and it remains a serious worldwide health issue. Because of their capacity to specifically target cancer cells and deliver therapeutic chemicals directly to them, nanoparticles have emerged as a viable strategy for cancer therapies. Nanomaterials disclose novel properties based on size, distribution, and shape. Biosynthesized or biogenic nanoparticles are a novel technique with anti-cancer capabilities, such as triggering apoptosis in cancer cells and slowing tumour growth. They may be configured to deliver medications or other therapies to specific cancer cells or tumour markers. Despite their potential, biosynthesized nanoparticles confront development obstacles such as a lack of standardisation in their synthesis and characterization, the possibility of toxicity, and their efficiency against various forms of cancer. The effectiveness and safety of biosynthesized nanoparticles must be further investigated, as well as the types of cancer they are most successful against. This review discusses the promise of biosynthesized nanoparticles as a novel approach for cancer therapeutics, as well as their mode of action and present barriers to their development. Frontiers Media S.A. 2023-07-13 /pmc/articles/PMC10374256/ /pubmed/37521721 http://dx.doi.org/10.3389/fmedt.2023.1236107 Text en © 2023 Chaturvedi, Sharma, Tripathi, Yadav, Singh, Singh and Singh. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medical Technology
Chaturvedi, Vivek K.
Sharma, Bhaskar
Tripathi, Abhay Dev
Yadav, Dawesh P.
Singh, Kshitij RB
Singh, Jay
Singh, Ravindra Pratap
Biosynthesized nanoparticles: a novel approach for cancer therapeutics
title Biosynthesized nanoparticles: a novel approach for cancer therapeutics
title_full Biosynthesized nanoparticles: a novel approach for cancer therapeutics
title_fullStr Biosynthesized nanoparticles: a novel approach for cancer therapeutics
title_full_unstemmed Biosynthesized nanoparticles: a novel approach for cancer therapeutics
title_short Biosynthesized nanoparticles: a novel approach for cancer therapeutics
title_sort biosynthesized nanoparticles: a novel approach for cancer therapeutics
topic Medical Technology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374256/
https://www.ncbi.nlm.nih.gov/pubmed/37521721
http://dx.doi.org/10.3389/fmedt.2023.1236107
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