Cargando…

Eleven key measures for monitoring general practice clinical activity during COVID-19: A retrospective cohort study using 48 million adults’ primary care records in England through OpenSAFELY

BACKGROUND: The COVID-19 pandemic has had a significant impact on delivery of NHS care. We have developed the OpenSAFELY Service Restoration Observatory (SRO) to develop key measures of primary care activity and describe the trends in these measures throughout the COVID-19 pandemic. METHODS: With th...

Descripción completa

Detalles Bibliográficos
Autores principales: Fisher, Louis, Curtis, Helen J, Croker, Richard, Wiedemann, Milan, Speed, Victoria, Wood, Christopher, Brown, Andrew, Hopcroft, Lisa EM, Higgins, Rose, Massey, Jon, Inglesby, Peter, Morton, Caroline E, Walker, Alex J, Morley, Jessica, Mehrkar, Amir, Bacon, Seb, Hickman, George, Macdonald, Orla, Lewis, Tom, Wood, Marion, Myers, Martin, Samuel, Miriam, Conibere, Robin, Baqir, Wasim, Sood, Harpreet, Drury, Charles, Collison, Kiren, Bates, Chris, Evans, David, Dillingham, Iain, Ward, Tom, Davy, Simon, Smith, Rebecca M, Hulme, William, Green, Amelia, Parry, John, Hester, Frank, Harper, Sam, Cockburn, Jonathan, O'Hanlon, Shaun, Eavis, Alex, Jarvis, Richard, Avramov, Dima, Griffiths, Paul, Fowles, Aaron, Parkes, Nasreen, MacKenna, Brian, Goldacre, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374277/
https://www.ncbi.nlm.nih.gov/pubmed/37498081
http://dx.doi.org/10.7554/eLife.84673
_version_ 1785078739374178304
author Fisher, Louis
Curtis, Helen J
Croker, Richard
Wiedemann, Milan
Speed, Victoria
Wood, Christopher
Brown, Andrew
Hopcroft, Lisa EM
Higgins, Rose
Massey, Jon
Inglesby, Peter
Morton, Caroline E
Walker, Alex J
Morley, Jessica
Mehrkar, Amir
Bacon, Seb
Hickman, George
Macdonald, Orla
Lewis, Tom
Wood, Marion
Myers, Martin
Samuel, Miriam
Conibere, Robin
Baqir, Wasim
Sood, Harpreet
Drury, Charles
Collison, Kiren
Bates, Chris
Evans, David
Dillingham, Iain
Ward, Tom
Davy, Simon
Smith, Rebecca M
Hulme, William
Green, Amelia
Parry, John
Hester, Frank
Harper, Sam
Cockburn, Jonathan
O'Hanlon, Shaun
Eavis, Alex
Jarvis, Richard
Avramov, Dima
Griffiths, Paul
Fowles, Aaron
Parkes, Nasreen
MacKenna, Brian
Goldacre, Ben
author_facet Fisher, Louis
Curtis, Helen J
Croker, Richard
Wiedemann, Milan
Speed, Victoria
Wood, Christopher
Brown, Andrew
Hopcroft, Lisa EM
Higgins, Rose
Massey, Jon
Inglesby, Peter
Morton, Caroline E
Walker, Alex J
Morley, Jessica
Mehrkar, Amir
Bacon, Seb
Hickman, George
Macdonald, Orla
Lewis, Tom
Wood, Marion
Myers, Martin
Samuel, Miriam
Conibere, Robin
Baqir, Wasim
Sood, Harpreet
Drury, Charles
Collison, Kiren
Bates, Chris
Evans, David
Dillingham, Iain
Ward, Tom
Davy, Simon
Smith, Rebecca M
Hulme, William
Green, Amelia
Parry, John
Hester, Frank
Harper, Sam
Cockburn, Jonathan
O'Hanlon, Shaun
Eavis, Alex
Jarvis, Richard
Avramov, Dima
Griffiths, Paul
Fowles, Aaron
Parkes, Nasreen
MacKenna, Brian
Goldacre, Ben
author_sort Fisher, Louis
collection PubMed
description BACKGROUND: The COVID-19 pandemic has had a significant impact on delivery of NHS care. We have developed the OpenSAFELY Service Restoration Observatory (SRO) to develop key measures of primary care activity and describe the trends in these measures throughout the COVID-19 pandemic. METHODS: With the approval of NHS England, we developed an open source software framework for data management and analysis to describe trends and variation in clinical activity across primary care electronic health record (EHR) data on 48 million adults. We developed SNOMED-CT codelists for key measures of primary care clinical activity such as blood pressure monitoring and asthma reviews, selected by an expert clinical advisory group and conducted a population cohort-based study to describe trends and variation in these measures January 2019-December 2021, and pragmatically classified their level of recovery one year into the pandemic using the percentage change in the median practice level rate. RESULTS: We produced 11 measures reflective of clinical activity in general practice. A substantial drop in activity was observed in all measures at the outset of the COVID-19 pandemic. By April 2021, the median rate had recovered to within 15% of the median rate in April 2019 in six measures. The remaining measures showed a sustained drop, ranging from a 18.5% reduction in medication reviews to a 42.0% reduction in blood pressure monitoring. Three measures continued to show a sustained drop by December 2021. CONCLUSIONS: The COVID-19 pandemic was associated with a substantial change in primary care activity across the measures we developed, with recovery in most measures. We delivered an open source software framework to describe trends and variation in clinical activity across an unprecedented scale of primary care data. We will continue to expand the set of key measures to be routinely monitored using our publicly available NHS OpenSAFELY SRO dashboards with near real-time data. FUNDING: This research used data assets made available as part of the Data and Connectivity National Core Study, led by Health Data Research UK in partnership with the Office for National Statistics and funded by UK Research and Innovation (grant ref MC_PC_20058).The OpenSAFELY Platform is supported by grants from the Wellcome Trust (222097/Z/20/Z); MRC (MR/V015757/1, MC_PC-20059, MR/W016729/1); NIHR (NIHR135559, COV-LT2-0073), and Health Data Research UK (HDRUK2021.000, 2021.0157).
format Online
Article
Text
id pubmed-10374277
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher eLife Sciences Publications, Ltd
record_format MEDLINE/PubMed
spelling pubmed-103742772023-07-28 Eleven key measures for monitoring general practice clinical activity during COVID-19: A retrospective cohort study using 48 million adults’ primary care records in England through OpenSAFELY Fisher, Louis Curtis, Helen J Croker, Richard Wiedemann, Milan Speed, Victoria Wood, Christopher Brown, Andrew Hopcroft, Lisa EM Higgins, Rose Massey, Jon Inglesby, Peter Morton, Caroline E Walker, Alex J Morley, Jessica Mehrkar, Amir Bacon, Seb Hickman, George Macdonald, Orla Lewis, Tom Wood, Marion Myers, Martin Samuel, Miriam Conibere, Robin Baqir, Wasim Sood, Harpreet Drury, Charles Collison, Kiren Bates, Chris Evans, David Dillingham, Iain Ward, Tom Davy, Simon Smith, Rebecca M Hulme, William Green, Amelia Parry, John Hester, Frank Harper, Sam Cockburn, Jonathan O'Hanlon, Shaun Eavis, Alex Jarvis, Richard Avramov, Dima Griffiths, Paul Fowles, Aaron Parkes, Nasreen MacKenna, Brian Goldacre, Ben eLife Epidemiology and Global Health BACKGROUND: The COVID-19 pandemic has had a significant impact on delivery of NHS care. We have developed the OpenSAFELY Service Restoration Observatory (SRO) to develop key measures of primary care activity and describe the trends in these measures throughout the COVID-19 pandemic. METHODS: With the approval of NHS England, we developed an open source software framework for data management and analysis to describe trends and variation in clinical activity across primary care electronic health record (EHR) data on 48 million adults. We developed SNOMED-CT codelists for key measures of primary care clinical activity such as blood pressure monitoring and asthma reviews, selected by an expert clinical advisory group and conducted a population cohort-based study to describe trends and variation in these measures January 2019-December 2021, and pragmatically classified their level of recovery one year into the pandemic using the percentage change in the median practice level rate. RESULTS: We produced 11 measures reflective of clinical activity in general practice. A substantial drop in activity was observed in all measures at the outset of the COVID-19 pandemic. By April 2021, the median rate had recovered to within 15% of the median rate in April 2019 in six measures. The remaining measures showed a sustained drop, ranging from a 18.5% reduction in medication reviews to a 42.0% reduction in blood pressure monitoring. Three measures continued to show a sustained drop by December 2021. CONCLUSIONS: The COVID-19 pandemic was associated with a substantial change in primary care activity across the measures we developed, with recovery in most measures. We delivered an open source software framework to describe trends and variation in clinical activity across an unprecedented scale of primary care data. We will continue to expand the set of key measures to be routinely monitored using our publicly available NHS OpenSAFELY SRO dashboards with near real-time data. FUNDING: This research used data assets made available as part of the Data and Connectivity National Core Study, led by Health Data Research UK in partnership with the Office for National Statistics and funded by UK Research and Innovation (grant ref MC_PC_20058).The OpenSAFELY Platform is supported by grants from the Wellcome Trust (222097/Z/20/Z); MRC (MR/V015757/1, MC_PC-20059, MR/W016729/1); NIHR (NIHR135559, COV-LT2-0073), and Health Data Research UK (HDRUK2021.000, 2021.0157). eLife Sciences Publications, Ltd 2023-07-27 /pmc/articles/PMC10374277/ /pubmed/37498081 http://dx.doi.org/10.7554/eLife.84673 Text en © 2023, Fisher et al https://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Epidemiology and Global Health
Fisher, Louis
Curtis, Helen J
Croker, Richard
Wiedemann, Milan
Speed, Victoria
Wood, Christopher
Brown, Andrew
Hopcroft, Lisa EM
Higgins, Rose
Massey, Jon
Inglesby, Peter
Morton, Caroline E
Walker, Alex J
Morley, Jessica
Mehrkar, Amir
Bacon, Seb
Hickman, George
Macdonald, Orla
Lewis, Tom
Wood, Marion
Myers, Martin
Samuel, Miriam
Conibere, Robin
Baqir, Wasim
Sood, Harpreet
Drury, Charles
Collison, Kiren
Bates, Chris
Evans, David
Dillingham, Iain
Ward, Tom
Davy, Simon
Smith, Rebecca M
Hulme, William
Green, Amelia
Parry, John
Hester, Frank
Harper, Sam
Cockburn, Jonathan
O'Hanlon, Shaun
Eavis, Alex
Jarvis, Richard
Avramov, Dima
Griffiths, Paul
Fowles, Aaron
Parkes, Nasreen
MacKenna, Brian
Goldacre, Ben
Eleven key measures for monitoring general practice clinical activity during COVID-19: A retrospective cohort study using 48 million adults’ primary care records in England through OpenSAFELY
title Eleven key measures for monitoring general practice clinical activity during COVID-19: A retrospective cohort study using 48 million adults’ primary care records in England through OpenSAFELY
title_full Eleven key measures for monitoring general practice clinical activity during COVID-19: A retrospective cohort study using 48 million adults’ primary care records in England through OpenSAFELY
title_fullStr Eleven key measures for monitoring general practice clinical activity during COVID-19: A retrospective cohort study using 48 million adults’ primary care records in England through OpenSAFELY
title_full_unstemmed Eleven key measures for monitoring general practice clinical activity during COVID-19: A retrospective cohort study using 48 million adults’ primary care records in England through OpenSAFELY
title_short Eleven key measures for monitoring general practice clinical activity during COVID-19: A retrospective cohort study using 48 million adults’ primary care records in England through OpenSAFELY
title_sort eleven key measures for monitoring general practice clinical activity during covid-19: a retrospective cohort study using 48 million adults’ primary care records in england through opensafely
topic Epidemiology and Global Health
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374277/
https://www.ncbi.nlm.nih.gov/pubmed/37498081
http://dx.doi.org/10.7554/eLife.84673
work_keys_str_mv AT fisherlouis elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT curtishelenj elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT crokerrichard elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT wiedemannmilan elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT speedvictoria elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT woodchristopher elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT brownandrew elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT hopcroftlisaem elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT higginsrose elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT masseyjon elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT inglesbypeter elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT mortoncarolinee elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT walkeralexj elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT morleyjessica elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT mehrkaramir elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT baconseb elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT hickmangeorge elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT macdonaldorla elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT lewistom elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT woodmarion elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT myersmartin elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT samuelmiriam elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT conibererobin elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT baqirwasim elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT soodharpreet elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT drurycharles elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT collisonkiren elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT bateschris elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT evansdavid elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT dillinghamiain elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT wardtom elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT davysimon elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT smithrebeccam elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT hulmewilliam elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT greenamelia elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT parryjohn elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT hesterfrank elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT harpersam elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT cockburnjonathan elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT ohanlonshaun elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT eavisalex elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT jarvisrichard elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT avramovdima elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT griffithspaul elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT fowlesaaron elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT parkesnasreen elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT mackennabrian elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely
AT goldacreben elevenkeymeasuresformonitoringgeneralpracticeclinicalactivityduringcovid19aretrospectivecohortstudyusing48millionadultsprimarycarerecordsinenglandthroughopensafely