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Gαq-PKD/PKCμ signal regulating the nuclear export of HDAC5 to induce the IκB expression and limit the NF-κB-mediated inflammatory response essential for early pregnancy

Decidualization, denoting the transformation of endometrial stromal cells into specialized decidual cells, is a prerequisite for normal embryo implantation and a successful pregnancy in human. Here, we demonstrated that knockout of Gαq lead to an aberrantly enhanced inflammatory state during decidua...

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Detalles Bibliográficos
Autores principales: Jiang, Yufei, He, Yan, Liu, Songting, Li, Gaizhen, Chen, Dunjin, Deng, Wenbo, Li, Ping, Zhang, Ying, Wu, Jinxiang, Li, Jianing, Wang, Longmei, Lin, Jiajing, Wang, Haibin, Kong, Shuangbo, Shi, Guixiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374280/
https://www.ncbi.nlm.nih.gov/pubmed/37498654
http://dx.doi.org/10.7554/eLife.83083