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Deep thermal profiling for detection of functional proteoform groups

The complexity of the functional proteome extends considerably beyond the coding genome, resulting in millions of proteoforms. Investigation of proteoforms and their functional roles is important to understand cellular physiology and its deregulation in diseases but challenging to perform systematic...

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Detalles Bibliográficos
Autores principales: Kurzawa, Nils, Leo, Isabelle Rose, Stahl, Matthias, Kunold, Elena, Becher, Isabelle, Audrey, Anastasia, Mermelekas, Georgios, Huber, Wolfgang, Mateus, André, Savitski, Mikhail M., Jafari, Rozbeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374440/
https://www.ncbi.nlm.nih.gov/pubmed/36941476
http://dx.doi.org/10.1038/s41589-023-01284-8