Rap1 organizes lymphocyte front-back polarity via RhoA signaling and talin1

Lymphocyte trafficking requires fine-tuning of chemokine-mediated cell migration. This process depends on cytoskeletal dynamics and polarity, but its regulation remains elusive. We quantitatively measured cell polarity and revealed critical roles performed by integrin activator Rap1 in this process,...

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Detalles Bibliográficos
Autores principales: Ueda, Yoshihiro, Higasa, Koichiro, Kamioka, Yuji, Kondo, Naoyuki, Horitani, Shunsuke, Ikeda, Yoshiki, Bergmeier, Wolfgang, Fukui, Yoshinori, Kinashi, Tatsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374465/
https://www.ncbi.nlm.nih.gov/pubmed/37520697
http://dx.doi.org/10.1016/j.isci.2023.107292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374465/
https://www.ncbi.nlm.nih.gov/pubmed/37520697
http://dx.doi.org/10.1016/j.isci.2023.107292

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