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Statins suppress cell-to-cell propagation of α-synuclein by lowering cholesterol
Cell-to-cell propagation of protein aggregates has been implicated in the progression of neurodegenerative diseases. However, the underlying mechanism and modulators of this process are not fully understood. Here, we screened a small-molecule library in a search for agents that suppress the propagat...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374525/ https://www.ncbi.nlm.nih.gov/pubmed/37500624 http://dx.doi.org/10.1038/s41419-023-05977-9 |