Cargando…

Pregnancy prevalence and outcomes after optic neuritis in South Korea

To compare pregnancy rates and complications in women with and without a history of optic neuritis (ON). A nationwide, population-based, retrospective study using data from the Korean National Health Claims from January 2011, to December 2017 was done. ON cohort (ON group) consisting of women aged 1...

Descripción completa

Detalles Bibliográficos
Autores principales: Choi, Daye Diana, Kim, Kyung-Ah, Park, Kyung-Ah, Oh, Sei Yeul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374557/
https://www.ncbi.nlm.nih.gov/pubmed/37500694
http://dx.doi.org/10.1038/s41598-023-38851-x
_version_ 1785078799156641792
author Choi, Daye Diana
Kim, Kyung-Ah
Park, Kyung-Ah
Oh, Sei Yeul
author_facet Choi, Daye Diana
Kim, Kyung-Ah
Park, Kyung-Ah
Oh, Sei Yeul
author_sort Choi, Daye Diana
collection PubMed
description To compare pregnancy rates and complications in women with and without a history of optic neuritis (ON). A nationwide, population-based, retrospective study using data from the Korean National Health Claims from January 2011, to December 2017 was done. ON cohort (ON group) consisting of women aged 18 to 50 with a history of ON and 1:3 age-matched controls (control group) were compared for pregnancy and delivery rates using logistic regression after adjusting for possible confounders. Pregnancy-ON cohort (pregnancy-ON group), women aged 18 to 55 with a history of ON and pregnancy, and 1:3 age at pregnancy matched controls (pregnancy-control group) were analyzed for pregnancy complications using logistic regression after adjusting for covariates. ON group (n = 2516) showed decreased odds ratio (OR) for pregnancy [Adjusted OR2: 0.716, 95% confidence interval (CI): 0.626–0.820] and delivery (adjusted OR2: 0.647, 95% CI: 0.554–0.756) compared to controls (n = 7548). Pregnancy-ON group (n = 550) showed increased risk of delayed fetal growth (adjusted OR2: 9.867, 95% CI: 1.224–79.564), pre-eclampsia (adjusted OR2: 8.327, 95% CI: 2.911–23.819), preterm delivery (adjusted OR2: 3.914, 95% CI: 2.667–5.742), pregnancy and postpartum infection (adjusted OR1: 1.671, 95% CI: 1.296–2.154), diabetes in pregnancy (adjusted OR2: 1.365, 95% CI: 1.062–1.754) compared to pregnancy-control group (n = 1650). Our population-based cohort study suggests that history of ON is associated with decreased pregnancy and delivery rates. It may be a risk factor for various pregnancy complications.
format Online
Article
Text
id pubmed-10374557
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-103745572023-07-29 Pregnancy prevalence and outcomes after optic neuritis in South Korea Choi, Daye Diana Kim, Kyung-Ah Park, Kyung-Ah Oh, Sei Yeul Sci Rep Article To compare pregnancy rates and complications in women with and without a history of optic neuritis (ON). A nationwide, population-based, retrospective study using data from the Korean National Health Claims from January 2011, to December 2017 was done. ON cohort (ON group) consisting of women aged 18 to 50 with a history of ON and 1:3 age-matched controls (control group) were compared for pregnancy and delivery rates using logistic regression after adjusting for possible confounders. Pregnancy-ON cohort (pregnancy-ON group), women aged 18 to 55 with a history of ON and pregnancy, and 1:3 age at pregnancy matched controls (pregnancy-control group) were analyzed for pregnancy complications using logistic regression after adjusting for covariates. ON group (n = 2516) showed decreased odds ratio (OR) for pregnancy [Adjusted OR2: 0.716, 95% confidence interval (CI): 0.626–0.820] and delivery (adjusted OR2: 0.647, 95% CI: 0.554–0.756) compared to controls (n = 7548). Pregnancy-ON group (n = 550) showed increased risk of delayed fetal growth (adjusted OR2: 9.867, 95% CI: 1.224–79.564), pre-eclampsia (adjusted OR2: 8.327, 95% CI: 2.911–23.819), preterm delivery (adjusted OR2: 3.914, 95% CI: 2.667–5.742), pregnancy and postpartum infection (adjusted OR1: 1.671, 95% CI: 1.296–2.154), diabetes in pregnancy (adjusted OR2: 1.365, 95% CI: 1.062–1.754) compared to pregnancy-control group (n = 1650). Our population-based cohort study suggests that history of ON is associated with decreased pregnancy and delivery rates. It may be a risk factor for various pregnancy complications. Nature Publishing Group UK 2023-07-27 /pmc/articles/PMC10374557/ /pubmed/37500694 http://dx.doi.org/10.1038/s41598-023-38851-x Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Choi, Daye Diana
Kim, Kyung-Ah
Park, Kyung-Ah
Oh, Sei Yeul
Pregnancy prevalence and outcomes after optic neuritis in South Korea
title Pregnancy prevalence and outcomes after optic neuritis in South Korea
title_full Pregnancy prevalence and outcomes after optic neuritis in South Korea
title_fullStr Pregnancy prevalence and outcomes after optic neuritis in South Korea
title_full_unstemmed Pregnancy prevalence and outcomes after optic neuritis in South Korea
title_short Pregnancy prevalence and outcomes after optic neuritis in South Korea
title_sort pregnancy prevalence and outcomes after optic neuritis in south korea
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374557/
https://www.ncbi.nlm.nih.gov/pubmed/37500694
http://dx.doi.org/10.1038/s41598-023-38851-x
work_keys_str_mv AT choidayediana pregnancyprevalenceandoutcomesafteropticneuritisinsouthkorea
AT kimkyungah pregnancyprevalenceandoutcomesafteropticneuritisinsouthkorea
AT parkkyungah pregnancyprevalenceandoutcomesafteropticneuritisinsouthkorea
AT ohseiyeul pregnancyprevalenceandoutcomesafteropticneuritisinsouthkorea