Cargando…

THOC3 interacts with YBX1 to promote lung squamous cell carcinoma progression through PFKFB4 mRNA modification

The THO complex (THOC) is ubiquitously involved in RNA modification and various THOC proteins have been reported to regulate tumor development. However, the role of THOC3 in lung cancer remains unknown. In this study, we identified that THOC3 was highly expressed in lung squamous cell carcinoma (LUS...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Tao, Zhang, Qi, Yu, Shao-Kun, Nie, Feng-Qi, Zhang, Mei-Ling, Wang, Qian, Lu, Kai-Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374565/ https://www.ncbi.nlm.nih.gov/pubmed/37500615 http://dx.doi.org/10.1038/s41419-023-06008-3

Ejemplares similares

THOC2 and THOC5 Regulate Stemness and Radioresistance in Triple‐Negative Breast Cancer
por: Bai, Xupeng, et al.
Publicado: (2021)

Mechanisms of mRNA processing defects in inherited THOC6 intellectual disability syndrome
por: Werren, Elizabeth, et al.
Publicado: (2023)

Knockdown THOC2 suppresses the proliferation and invasion of melanoma
por: Zhou, Xiaowei, et al.
Publicado: (2019)

Expanding Clinical Presentations Due to Variations in THOC2 mRNA Nuclear Export Factor
por: Kumar, Raman, et al.
Publicado: (2020)

THOC5/FMIP, an mRNA export TREX complex protein, is essential for hematopoietic primitive cell survival in vivo
por: Mancini, Annalisa, et al.
Publicado: (2010)

Knockdown of THOC1 reduces the proliferation of hepatocellular carcinoma and increases the sensitivity to cisplatin
por: Cai, Shijiao, et al.
Publicado: (2020)

THOC5, a member of the mRNA export complex: a novel link between mRNA export machinery and signal transduction pathways in cell proliferation and differentiation
por: Tran, Doan D H, et al.
Publicado: (2014)

Intellectual disability associated with a homozygous missense mutation in THOC6
por: Beaulieu, Chandree L, et al.
Publicado: (2013)

A Potential Oncogenic Role for PFKFB3 Overexpression in Gastric Cancer Progression
por: Lei, Lan, et al.
Publicado: (2021)

YBX1 promotes tumor progression via the PI3K/AKT signaling pathway in laryngeal squamous cell carcinoma
por: Zhao, Jing, et al.
Publicado: (2021)

Comparative clinical significance and biological roles of PFKFB family members in oral squamous cell carcinoma
por: Hu, Kai-Fang, et al.
Publicado: (2023)

Differential expression of THOC1 and ALY mRNP biogenesis/export factors in human cancers
por: Domínguez-Sánchez, María S, et al.
Publicado: (2011)

Transcriptional regulation of immediate-early gene response by THOC5, a member of mRNA export complex, contributes to the M-CSF-induced macrophage differentiation
por: Tran, D DH, et al.
Publicado: (2013)

YBX1 mediates alternative splicing and maternal mRNA decay during pre-implantation development
por: Deng, Mingtian, et al.
Publicado: (2022)

Role of PFKFB3 and PFKFB4 in Cancer: Genetic Basis, Impact on Disease Development/Progression, and Potential as Therapeutic Targets
por: Kotowski, Krzysztof, et al.
Publicado: (2021)

THOC1 deficiency leads to late-onset nonsyndromic hearing loss through p53-mediated hair cell apoptosis
por: Zhang, Luping, et al.
Publicado: (2020)

The Thoc1 Encoded Ribonucleoprotein Is Required for Myeloid Progenitor Cell Homeostasis in the Adult Mouse
por: Pitzonka, Laura, et al.
Publicado: (2014)

THOC5, a member of the mRNA export complex, contributes to processing of a subset of wingless/integrated (Wnt) target mRNAs and integrity of the gut epithelial barrier
por: Saran, Shashank, et al.
Publicado: (2013)

RNA-binding protein YBX1 promotes cell proliferation and invasiveness of nasopharyngeal carcinoma cells via binding to AURKA mRNA
por: Ban, Yuanyuan, et al.
Publicado: (2021)

Comparison of Protamine 1 to Protamine 2 mRNA Ratio and YBX2 gene mRNA Content in Testicular Tissue of Fertile and Azoospermic Men
por: Moghbelinejad, Sahar, et al.
Publicado: (2015)

Phosphorylated YBX2 is stabilized to promote glycolysis in brown adipocytes
por: Zhao, Qingwen, et al.
Publicado: (2023)

The Pleiotropic Effects of YBX1 on HTLV-1 Transcription
por: Smith, Susan, et al.
Publicado: (2023)

Blockage of glycolysis by targeting PFKFB3 suppresses tumor growth and metastasis in head and neck squamous cell carcinoma
por: Li, Hui-Min, et al.
Publicado: (2017)

LncRNA FOXD3-AS1 Promotes the Malignant Progression of Nasopharyngeal Carcinoma Through Enhancing the Transcription of YBX1 by H3K27Ac Modification
por: Yang, Huiyun, et al.
Publicado: (2021)

N(6)-methyladenosine modification of ITGA6 mRNA promotes the development and progression of bladder cancer
por: Jin, Huan, et al.
Publicado: (2019)

LNCAROD is stabilized by m6A methylation and promotes cancer progression via forming a ternary complex with HSPA1A and YBX1 in head and neck squamous cell carcinoma
por: Ban, Yuanyuan, et al.
Publicado: (2020)

Roles of PFKFB3 in cancer
por: Shi, Linlin, et al.
Publicado: (2017)

Inhibition of PFKFB3 Hampers the Progression of Atherosclerosis and Promotes Plaque Stability
por: Poels, Kikkie, et al.
Publicado: (2020)

Therapeutic targeting of PFKFB3 and PFKFB4 in multiple myeloma cells under hypoxic conditions
por: Okabe, Seiichi, et al.
Publicado: (2022)

YBX1‐Mediated DNA Methylation‐Dependent SHANK3 Expression in PBMCs and Developing Cortical Interneurons in Schizophrenia
por: Ni, Peiyan, et al.
Publicado: (2023)

CTPS1 promotes malignant progression of triple-negative breast cancer with transcriptional activation by YBX1
por: Lin, Yuxiang, et al.
Publicado: (2022)

A novel positive feedback loop of linc02042 and c-Myc mediated by YBX1 promotes tumorigenesis and metastasis in esophageal squamous cell carcinoma
por: Du, Jiahui, et al.
Publicado: (2020)

YBX1 as an oncogenic factor in T-cell acute lymphoblastic leukemia
por: Li, Huan, et al.
Publicado: (2023)

LINC00312/YBX1 Axis Regulates Myofibroblast Activities in Oral Submucous Fibrosis
por: Yu, Chuan-Hang, et al.
Publicado: (2020)

Long non-coding RNA CASC11 interacts with YBX1 to promote prostate cancer progression by suppressing the p53 pathway
por: Sun, Xianchao, et al.
Publicado: (2022)

SIAH1 reverses chemoresistance in epithelial ovarian cancer via ubiquitination of YBX-1
por: Gao, Wujiang, et al.
Publicado: (2022)

Evaluation of mRNA Contents of YBX2 and JHDM2A Genes on Testicular Tissues of Azoospermic Men with Different Classes of Spermatogenesis
por: Najafipour, Reza, et al.
Publicado: (2015)

YBX1 Indirectly Targets Heterochromatin-Repressed Inflammatory Response-Related Apoptosis Genes through Regulating CBX5 mRNA
por: Kloetgen, Andreas, et al.
Publicado: (2020)

PFKFB3: A Potential Key to Ocular Angiogenesis
por: Zhou, Zi-Yi, et al.
Publicado: (2021)

CBX3 Regulated By YBX1 Promotes Smoking-induced Pancreatic Cancer Progression via Inhibiting SMURF2 Expression
por: Zhang, Huan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_l5jnidh454uprvh9rugrlqfet2